منابع مشابه
Microtubules shape the cell
How to make a lysosome oated vesicles had been described as early as 1961. These small membranous structures were characterized by a highly organized layer of material on the cytoplasmic surface, “but no one knew their function,” says Marilyn Farquhar, whose lab at the time had become interested in how the Golgi complex helped produce enzymes. Roth and Porter (1964) had provided evidence that c...
متن کاملMicrotubules and control of insect egg shape
This study evidence for tension transmission by microtubules and desmosomes in the follicular epithelium during anisometric growth of certain insect eggs. Most insect oocytes, and the follicles which surround them, grow anisometrically as they assume shapes which approximate to those of long prolate spheroids. Surface growth is most rapid in directions which parallel the polar axis of an oocyte...
متن کاملSpatio-temporal orientation of microtubules controls conical cell shape in Arabidopsis thaliana petals
The physiological functions of epidermal cells are largely determined by their diverse morphologies. Most flowering plants have special conical-shaped petal epidermal cells that are thought to influence light capture and reflectance, and provide pollinator grips, but the molecular mechanisms controlling conical cell shape remain largely unknown. Here, we developed a live-confocal imaging approa...
متن کاملComplex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells.
Translationally controlled tumor-associated protein (TCTP) is a ubiquitous and highly conserved protein implicated in cancers. Here, we demonstrate that interactions of TCTP with microtubules (MTs) are functionally important but indirect, and we reveal novel interaction of TCTP with the actin cytoskeleton. Firstly, immunofluorescence in Xenopus XL2 cells revealed cytoplasmic fibers stained with...
متن کاملTorsinA, microtubules and cell polarity.
Early-onset primary dystonia is an inherited disorder characterized by involuntary twisting, repetitive movements and abnormal postures. It has recently been demonstrated that the DYT1 gene is the most relevant gene associated with primary generalized dystonia. The DYT1 gene product is a 332-aminoacid long protein, termed TorsinA, whose function is still not clear. Based on the results obtained...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2005
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1694fta2